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2007-06-18Bioconductorチュートリアル @ NIG

はじめに はじめに - Bioconductorノート を含むブックマーク はてなブックマーク - はじめに - Bioconductorノート はじめに - Bioconductorノート のブックマークコメント

目次

  • はじめに
    • このチュートリアルの概略
    • 参考資料

このチュートリアルは、生物学研究者向けにBioconductorのできることとできないことを概説し、遺伝子発現データからの解析のケーススタディを紹介します。各話題は一時間程度で終わるようになっています。また、R 2.4Bioconductor 1.9 で実行可能なコードを用いています。


このチュートリアルは、「RとBioConductorを用いたバイオインフォマティクス」(シュプリンガージャパン 7月出版予定)にもとづいています。


このチュートリアルの概略

  1. R の導入についてではRとBioconductorの導入方法について説明します。
  2. Bioconductor の紹介では、Bioconductorのできることとできないこと、簡単なBioconductorの使用例、そしてこのチュートリアルのあとに見るべき資料について説明します。
  3. ケーススタディ:遺伝子発現データの分類では、遺伝子発現データを用いた典型的な解析のひとつである、遺伝子発現からの細胞(フェノタイプ)の分類の研究について例を示して、データから分類結果までの流れとそこで用いられる Bioconductor の機能について説明します。
  4. ケーススタディ:CELファイルから興味ある遺伝子リストの作成では、Affymetrix DNA chip解析データCELファイル)から注目している条件下で発現変動を示す遺伝子リスト選別し、その遺伝子リストアノテーションメタデータ)を関連づけし、レポートを作成するまでの解析の流れとそこでもちいられる Bioconductor の機能について説明します。

参考資料

  1. 「RとBioConductorを用いたバイオインフォマティクス」(シュプリンガージャパン 7月出版予定)
  2. Bioconductor - Help
    1. http://www.bioconductor.org/mogr/chapter-code/class.R
    2. http://www.bioconductor.org/mogr/chapter-code/fromcels.R
    3. Bioconductor - Getting the Monograph via R
    4. Bioconductor - Data

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